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Oncology Glossary

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quality-adjusted-life-year (QALY): a common measure of health improvement used in economic evaluation that measures life expectancy adjusted for quality of life.

quality improvement: a continuous process that employs rapid cycles of improvement of quality of care, particularly regarding settings where care is delivered, following of good medical practices, and impact on health status.

quantitative polymerase chain reaction (qPCR): process used in detecting polymerase chain reaction products as they accumulate that can be applied to gene expression quantification by reverse transcription of RNA into cDNA. In spite of its name (ie, quantitative), results are usually normalized to an endogenous reference. Devices allow the simultaneous assessment of many RNA sequences.

quantitative real-time polymerase chain reaction (RT-PCR): process used in detecting polymerase chain reaction products as they accumulate that can be applied to gene expression quantification by reverse transcription of RNA into cDNA. In spite of its name (ie, quantitative), results are usually normalized to an endogenous reference. Devices allow the simultaneous assessment of many RNA sequences.

quantitative real-time polymerase chain reaction (QRT-PCR): process used in detecting polymerase chain reaction products as they accumulate that can be applied to gene expression quantification by reverse transcription of RNA into cDNA. In spite of its name (ie, quantitative) results are usually normalized to an endogenous reference. Devices allow the simultaneous assessment of many RNA sequences.

quasimonomorphic loci: noncoding microsatellites with very small differences (not exceeding 1 or 2 base pairs) between the different alleles in different individuals, making these loci almost monomorphic. They can be highly unstable in microsatellite instability tumors where they present important size differences as compared with their normal quasimonomorphic size.


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