Journal of Clinical Oncology  
Search for:
Limit by:
  Browse by Subject or Issue
Home Search or Browse JCO My JCO Subscriptions Customer Service Site Map

JCO Early Release, published online ahead of print Jan 17 2012
Journal of Clinical Oncology, 10.1200/JCO.2011.37.0437

This Article
Right arrow Full Text (PDF)
Right arrow Data Supplement
Right arrow Purchase Article
Right arrow View Shopping Cart
Right arrow Alert me when this article is cited
Right arrow Alert me if a correction is posted
Right arrow Email this article to a colleague
Right arrow Similar articles in this journal
Right arrow Similar articles in PubMed
Right arrow Alert me to new issues of the journal
Right arrow Save to my personal folders
Right arrow Download to citation manager
Right arrowRights & Permissions
Citing Articles
Right arrow Citing Articles via HighWire
Right arrow Citing Articles via Google Scholar
Google Scholar
Right arrow Articles by Sheinfeld Gorin, S.
Right arrow Articles by Jacobsen, P. B.
Right arrow Search for Related Content
Right arrow PubMed Citation
Right arrow Articles by Sheinfeld Gorin, S.
Right arrow Articles by Jacobsen, P. B.
Social Bookmarking
 Add to CiteULike   Add to Complore   Add to Connotea   Add to Delicious   Add to Digg   Add to Facebook   Add to Reddit   Add to Technorati   Add to Twitter  
What's this?

Palliative and Supportive Care

Submitted May 13, 2011; accepted November 8, 2011.

Meta-Analysis of Psychosocial Interventions to Reduce Pain in Patients With Cancer

Sherri Sheinfeld Gorin, Paul Krebs, Hoda Badr, Elizabeth Amy Janke, Heather S.L. Jim, Bonnie Spring, David C. Mohr, Mark A. Berendsen, Paul B. Jacobsen

Sherri Sheinfeld Gorin, Herbert Irving Comprehensive Cancer Center, Columbia University; Paul Krebs, New York University School of Medicine; Hoda Badr, Mount Sinai School of Medicine, New York, NY; Elizabeth Amy Janke, University of the Sciences, Philadelphia, PA; Heather S.L. Jim and Paul B. Jacobsen, H. Lee Moffitt Cancer Center & Research Institute, Tampa, FL; Bonnie Spring and Mark A. Berendsen, Northwestern University; and David C. Mohr, Northwestern University, Feinberg School of Medicine, Chicago, IL.

Corresponding author: Paul Jacobsen, PhD, Department of Health Outcomes and Behavior, H. Lee Moffitt Cancer Center and Research Institute, Tampa, FL 33612; e-mail: paul.jacobsen{at}

Purpose Pain is one of the most common, burdensome, and feared symptoms experienced by patients with cancer. American Pain Society standards for pain management in cancer recommend both pharmacologic and psychosocial approaches. To obtain a current, stable, and comprehensive estimate of the effect of psychosocial interventions on pain—an important clinical topic—we conducted a meta-analysis of randomized controlled studies among adult patients with cancer published between 1966 and 2010.

Methods Three pairs of raters independently reviewed 1,681 abstracts, with a systematic process for reconciling disagreement, yielding 42 papers, of which 37 had sufficient data for meta-analysis. Studies were assessed for quality using a modified seven-item Physiotherapy Evidence Database (PEDro) coding scheme. Pain severity and interference were primary outcome measures.

Results Study participants (N = 4,199) were primarily women (66%) and white (72%). The weighted averaged effect size across studies for pain severity (38 comparisons) was 0.34 (95% CI, 0.23 to 0.46; P < .001), and the effect size for pain interference (four comparisons) was 0.40 (95% CI, 0.21 to 0.60; P < .001). Studies that monitored whether treatment was delivered as intended had larger effects than those that did not (P = .04).

Conclusion Psychosocial interventions had medium-size effects on both pain severity and interference. These robust findings support the systematic implementation of quality-controlled psychosocial interventions as part of a multimodal approach to the management of pain in patients with cancer.

Add to CiteULike CiteULike   Add to Complore Complore   Add to Connotea Connotea   Add to Delicious Delicious   Add to Digg Digg   Add to Facebook Facebook   Add to Reddit Reddit   Add to Technorati Technorati   Add to Twitter Twitter    What's this?

This article has been cited by other articles:

Home page
Palliat MedHome page
R. C. Hill, M. Dempster, M. Donnelly, and N. K. McCorry
Improving the wellbeing of staff who work in palliative care settings: A systematic review of psychosocial interventions
Palliative Medicine, October 1, 2016; 30(9): 825 - 833.
[Abstract] [Full Text] [PDF]

Home page
JCOHome page
J. E. Bower
Mindfulness Interventions for Cancer Survivors: Moving Beyond Wait-List Control Groups
J. Clin. Oncol., October 1, 2016; 34(28): 3366 - 3368.
[Full Text] [PDF]

Home page
International Journal of Qualitative MethodsHome page
K. Flemming, S. J. Closs, N. D. Hughes, and M. I. Bennett
Using Qualitative Research to Overcome the Shortcomings of Systematic Reviews When Designing of a Self-Management Intervention for Advanced Cancer Pain
International Journal of Qualitative Methods, September 23, 2016; 15(1): 1609406916670656 - 1609406916670656.
[Abstract] [Full Text] [PDF]

Home page
JCOHome page
J. A. Paice, R. Portenoy, C. Lacchetti, T. Campbell, A. Cheville, M. Citron, L. S. Constine, A. Cooper, P. Glare, F. Keefe, et al.
Management of Chronic Pain in Survivors of Adult Cancers: American Society of Clinical Oncology Clinical Practice Guideline
J. Clin. Oncol., September 20, 2016; 34(27): 3325 - 3345.
[Abstract] [Full Text] [PDF]

Home page
Nicotine Tob ResHome page
C. J. Aigner, P. M. Cinciripini, K. O. Anderson, G. P. Baum, E. R. Gritz, and C. Y. Lam
The Association of Pain With Smoking and Quit Attempts in an Electronic Diary Study of Cancer Patients Trying to Quit
Nicotine Tob Res, June 1, 2016; 18(6): 1449 - 1455.
[Abstract] [Full Text] [PDF]

Home page
BMJ Support Palliat CareHome page
P. Fitzgerald, C. Lo, M. Li, L. Gagliese, C. Zimmermann, and G. Rodin
The relationship between depression and physical symptom burden in advanced cancer
BMJ Supportive & Palliative Care, December 1, 2015; 5(4): 381 - 388.
[Abstract] [Full Text] [PDF]

Home page
JCOHome page
L. Wenzel, K. Osann, S. Hsieh, J. A. Tucker, B. J. Monk, and E. L. Nelson
Psychosocial Telephone Counseling for Survivors of Cervical Cancer: Results of a Randomized Biobehavioral Trial
J. Clin. Oncol., April 1, 2015; 33(10): 1171 - 1179.
[Abstract] [Full Text] [PDF]

Home page
JCOHome page
M. R. Lovell, T. Luckett, F. M. Boyle, J. Phillips, M. Agar, and P. M. Davidson
Patient Education, Coaching, and Self-Management for Cancer Pain
J. Clin. Oncol., June 1, 2014; 32(16): 1712 - 1720.
[Abstract] [Full Text] [PDF]

Home page
JCOHome page
K. L. Syrjala, M. P. Jensen, M. E. Mendoza, J. C. Yi, H. M. Fisher, and F. J. Keefe
Psychological and Behavioral Approaches to Cancer Pain Management
J. Clin. Oncol., June 1, 2014; 32(16): 1703 - 1711.
[Abstract] [Full Text] [PDF]

Home page
Arch. Dis. Child.Home page
D. Rajapakse, C. Liossi, and R. F. Howard
Presentation and management of chronic pain
Arch. Dis. Child., May 1, 2014; 99(5): 474 - 480.
[Abstract] [Full Text] [PDF]

Home page
J Natl Compr Canc NetwHome page
C. S. Denlinger, J. A. Ligibel, M. Are, K. S. Baker, W. Demark-Wahnefried, D. L. Friedman, M. Goldman, L. Jones, A. King, G. H. Ku, et al.
Survivorship: Pain Version 1.2014
J Natl Compr Canc Netw, April 1, 2014; 12(4): 488 - 500.
[Abstract] [Full Text] [PDF]

Home page
J Natl Compr Canc NetwHome page
R. A. Swarm, A. P. Abernethy, D. L. Anghelescu, C. Benedetti, S. Buga, C. Cleeland, O. A. deLeon-Casasola, J. G. Eilers, B. Ferrell, M. Green, et al.
Adult Cancer Pain
J Natl Compr Canc Netw, August 1, 2013; 11(8): 992 - 1022.
[Abstract] [Full Text] [PDF]

Home page
Br J AnaesthHome page
C. Eccleston, S. J. Morley, and A. C. d. C. Williams
Psychological approaches to chronic pain management: evidence and challenges
Br. J. Anaesth., July 1, 2013; 111(1): 59 - 63.
[Abstract] [Full Text] [PDF]

Home page
Journal WatchHome page
Barbara A. Murphy, MD and Barbara A. Murphy, MD
Do Psychosocial Interventions Reduce Pain in Cancer Patients?
Journal Watch, April 19, 2013; 2012(0): OH201202280000003 - OH201202280000003.
[Full Text]

Home page
JCOHome page
P. B. Jacobsen, J. C. Holland, and D. P. Steensma
Caring for the Whole Patient: The Science of Psychosocial Care
J. Clin. Oncol., April 10, 2012; 30(11): 1151 - 1153.
[Full Text] [PDF]

Home page
JWatch Oncology and HematologyHome page
Do Psychosocial Interventions Reduce Pain in Cancer Patients?
Journal Watch Oncology and Hematology, February 28, 2012; 2012(228): 3 - 3.
[Full Text]

 Librarians &
 Rights &
 PDA Services

Copyright © 2012 by the American Society of Clinical Oncology, Online ISSN: 1527-7755. Print ISSN: 0732-183X
Terms and Conditions of Use
  HighWire Press HighWire Press™ assists in the publication of JCO Online